Prism treatment plans based on fMRI and DTI studies deliver treatment that is faster, safer and more effective for the patient. Pre-treatment mapping identifies functional structures to avoid during treatment. Prism mapping speeds cortical localization using conventional electrode stimulation in the operating room. Avoiding functional structures during treatment dramatically reduces the risk and incidence of treatment-related deficits.

Prism's breakthrough imaging technology increases clinical productivity. Post processing that used to take hours is now done in minutes by trained technologists. Clinical interpretation is fast and accurate. Critical spatial relationships are established across multiple image volumes in a single view. The physician interface includes a powerful set of tools that are useful in validating data quality, highlighting regions of interest and identifying overlapping activation patterns.

Resources

Ulmer, Preoperative Diffusion Tensor Imaging: Improving Neurosurgical Outcomes in Brain Tumor Patients.

By establishing spatial relationships between lesion borders and functional networks preoperatively and intraoperatively, DTI is central to high-risk neurosurgical resections and becoming the standard of care..

Neuroimaging Clin N Am. 2014 Nov;24(4):599-617.

Vera, Postoperative morbidity and mortality with multi-layer, multi-parameter fMRI/DTI presurgical brain mapping: a retrospective, single-institution experience.

A study reiterating the benefits of fMRI and DTI in pre-surgical planning of tumors.

Congress of Neurological Surgeons 2012, poster 1345.


DeYoe, fMRI of Human Visual Pathways

Together, fMRI and DTI provide a wealth of information about the anatomical and functional status of key components of the visual system in individual patients even in the presence of pathology.

In: Functional Neuroradiology: Principles and Applications S. Faro and F. B. Mohamed. New York, Springer: 485-511


Holodny, Clinical Applications of fMRI and DTI.

Clinical Applications of fMRI and DTI. ISMRM 2006.


Petrella, Preoperative Functional MR Imaging Localization of Language and Motor Areas.

Preoperative Functional MR Imaging Localization of Language and Motor Areas: Effect on Therapeutic Decision Making in Patients with Potentially Resectable Brain Tumors.

Radiology 2006 240(3):793-802.


Chang, Neurocognition in patients treated with radiosurgery.

Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomized controlled trial.

Lancet Oncol. 2009 [Epub].


Schleim, fMRI in translation: the challenges facing real-world applications.

(Perspective article) fMRI in translation: the challenges facing real-world applications.

Frontiers in Human Neuroscience 2009 3(63).

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